Back in 2003, my ghost hunting team used a forum to communicate and arrange logistics and share our thoughts on various subjects. These cartoons were posted as “in” jokes about several topics that were going on at that time.
The first was about the subject of “orbs” which was being hotly debated back then. While most of us certain they were nothing more than photographic artifacts (dust) there were a few that thought that they could be ghosts. However the skeptical argument was a good one. So the debate among them was how could one determine if they were ghosts if they also looked like dust particles. While this debate was soon solved, this cartoon mysteriously appeared in the forum.
This was another, just a Southpark joke.
No explanation needed for this one.